exRNAdisease

Entry Detail

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General Information

Database ID: exR0022836 RNA Name: GLYR1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 4803203 End Site(bp): 4847288 External Links: ENSG00000140632

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABT1 chr6 26596953 26600739 + AC006486.1 chr19 42234583 42255132 - AC093525.2 chr16 2496032 2520218 + AC105052.3 chr7 102637049 102671641 - ACTG1 chr17 81509971 81523847 - AKT2 chr19 40230317 40285536 - AL121758.1 chr20 646626 675800 - AL136454.1 chr1 192716132 192716653 + ALDH1B1 chr9 38392702 38398661 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-28-5p chr3 188688794 188688815 + hsa-miR-147a chr9 120244985 120245004 - hsa-miR-671-5p chr7 151238449 151238471 + hsa-miR-339-3p chr7 1022955 1022977 - hsa-miR-708-5p chr11 79402077 79402099 - hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - AL135925.1 chr10 79825902 79827602 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA