exRNAdisease

Entry Detail

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General Information

Database ID: exR0023432 RNA Name: HLA-B RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31269491 End Site(bp): 31357188 External Links: ENSG00000234745

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTA2 chr10 88935074 88991339 - ACTG1 chr17 81509971 81523847 - ADPRHL2 chr1 36088892 36093932 + AK4 chr1 65147549 65232145 + AC092647.5 chr7 55887277 55955239 + ADM chr11 10305073 10307397 + AHCY chr20 34280268 34311802 - ACTB chr7 5527148 5563784 - ABCC10 chr6 43427366 43450427 + ACOT7 chr1 6264269 6394391 - ADAR chr1 154582057 154628013 - AGTRAP chr1 11736084 11754802 + ADI1 chr2 3497366 3519531 - AK2 chr1 33007940 33080996 - ABLIM1 chr10 114431113 114768061 - AC069503.2 chr12 121888809 121921470 + AL109827.1 chr20 35632340 35674544 - AGAP3 chr7 151085831 151144436 + AC011462.1 chr19 41350853 41425001 + AC135050.2 chr16 31083439 31094956 - AC046185.1 chr17 63702845 63752097 - ADRM1 chr20 62302093 62308862 + AC010422.3 chr19 12643831 12648397 - AC005258.1 chr19 2269525 2341172 + ADGRG2 chrX 18989307 19122637 - ACTR3 chr2 113890063 113962596 + ADCY1 chr7 45574140 45723116 + ACTA1 chr1 229431245 229434098 - ACADSB chr10 123008979 123058290 + AICDA chr12 8602170 8612867 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-6891-5p chr6 31355297 31355315 - hsa-miR-6516-5p chr17 77089428 77089449 + hsa-miR-6516-3p chr17 77089469 77089490 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC006942.1 chr19 49808933 49809738 + AC019205.1 chr6 73263212 73301789 + AC023509.1 chr12 53441741 53467528 + AC067852.2 chr17 42552436 42554748 - AC091564.7 chr11 6610883 6616594 - AC093157.1 chr1 101025844 101090513 + AC134043.2 chr5 159209921 159248796 + AC139530.1 chr17 81701324 81703300 - AC147651.4 chr7 603185 608482 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA