exRNAdisease

Entry Detail

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General Information

Database ID: exR0023462 RNA Name: HMGA1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 34236873 End Site(bp): 34246231 External Links: ENSG00000137309

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTR2 chr2 65227753 65271253 + ADNP chr20 50888916 50931437 - AKR7A2 chr1 19303965 19312146 - ADH5 chr4 99070978 99088801 - ADM chr11 10305073 10307397 + AC008982.1 chr19 38817471 38840178 - ADGRL1 chr19 14147743 14206187 - AGPAT1 chr6 32168212 32178096 - ADGRA3 chr4 22345071 22516066 - AGFG2 chr7 100539203 100568220 + ACLY chr17 41866917 41930542 - AJUBA chr14 22971177 22982551 - AK4 chr1 65147549 65232145 + AAMP chr2 218264123 218270257 - AC009133.6 chr16 29812261 29820092 + AHCYL2 chr7 129225023 129430211 + AC068547.1 chr2 151802651 151973949 - AC015813.2 chr17 57989038 58007246 - AKAP13 chr15 85380571 85749358 + AFTPH chr2 64524305 64593005 + AK5 chr1 77282019 77559966 + ADRM1 chr20 62302093 62308862 + ACER3 chr11 76860867 77026797 + AL121594.1 chr14 35122549 35317474 + ACTA1 chr1 229431245 229434098 - AHCY chr20 34280268 34311802 - ABRACL chr6 139028745 139043302 + ADARB1 chr21 45073853 45226560 + AL136454.1 chr1 192716132 192716653 + ACAD10 chr12 111686056 111757107 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-let-7d-5p chr9 94178841 94178862 + hsa-let-7e-5p chr19 51692793 51692814 + hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-138-5p chr16 56858527 56858549 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-6835-3p chr6 34240714 34240736 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC010331.1 chr19 47607873 47608454 - AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC020663.1 chr16 4730115 4752565 - AC020928.2 chr19 36773712 36775908 - AC025271.4 chr15 57553955 57555680 + AC079781.5 chr7 97851688 97972985 - AC104971.1 chr18 58670009 58671877 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL117378.1 chr6 131901963 131920565 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA