exRNAdisease

Entry Detail

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General Information

Database ID: exR0023471 RNA Name: HMGCS1 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 43287470 End Site(bp): 43313512 External Links: ENSG00000112972

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAAS chr12 53307456 53324864 - AC008575.1 chr5 112827213 112867582 + AC010646.1 chr19 17235940 17255448 - AC092143.1 chr16 89919165 89936092 + AC120057.2 chr17 7240427 7244635 - ACOT9 chrX 23701055 23766475 - ADAR chr1 154582057 154628013 - ADNP chr20 50888916 50931437 - AEBP1 chr7 44104345 44114562 + AGFG1 chr2 227472152 227561214 + AHCYL2 chr7 129225023 129430211 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7d-5p chr9 94178841 94178862 + hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-199a-5p chr1 172144592 172144614 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-199b-5p chr9 128244783 128244805 - hsa-miR-23b-3p chr9 95085265 95085287 + hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-296-3p chr20 58817626 58817647 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004847.1 chr7 44958999 44960909 - AC016876.2 chr17 7581964 7584086 - AC079781.5 chr7 97851688 97972985 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA