exRNAdisease

Entry Detail

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General Information

Database ID: exR0023641 RNA Name: HSP90B1 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 103930107 End Site(bp): 103953645 External Links: ENSG00000166598

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARS2 chr6 44298731 44313347 - AC010422.3 chr19 12643831 12648397 - AC099811.2 chr17 42119674 42154916 - AC135050.2 chr16 31083439 31094956 - AC139530.2 chr17 81703371 81720539 + ACTG1 chr17 81509971 81523847 - ACTG2 chr2 73892314 73919865 + ACTR2 chr2 65227753 65271253 + ADA2 chr22 17178790 17258235 - ADAM23 chr2 206443532 206621127 + ADCY6 chr12 48766194 48789037 - AFP chr4 73431138 73456174 + AKR1A1 chr1 45550543 45570049 + AL136454.1 chr1 192716132 192716653 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3652 chr12 103930425 103930442 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC022819.1 chr15 99157231 99161140 - AC068768.1 chr12 123262060 123262402 + AC108134.2 chr16 3156736 3157483 - AKT3-IT1 chr1 243793205 243794400 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA