exRNAdisease

Entry Detail

---



General Information

Database ID: exR0023650 RNA Name: HSPA4 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 133052013 End Site(bp): 133106449 External Links: ENSG00000170606

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABHD13 chr13 108218392 108234243 + ABRACL chr6 139028745 139043302 + AC002985.1 chr19 18907013 18934397 - AC092073.1 chr19 34396315 34409364 + AC124312.1 chr15 24955034 25000276 + ADPRM chr17 10697594 10711558 + AEN chr15 88621337 88632281 + AFAP1L1 chr5 149271859 149343637 + AGBL5 chr2 27042364 27070622 + AGPS chr2 177392757 177559299 + AHCYL1 chr1 109984765 110023742 + AIMP2 chr7 6009255 6023834 + AK3 chr9 4709556 4742043 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-302d-3p chr4 112648006 112648028 - hsa-miR-367-3p chr4 112647877 112647898 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA