exRNAdisease

Entry Detail

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General Information

Database ID: exR0023818 RNA Name: IGF1R RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 98648539 End Site(bp): 98964530 External Links: ENSG00000140443

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011005.1 chr7 129126518 129130793 + AC093525.1 chr16 2513965 2527955 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADARB1 chr21 45073853 45226560 + ADCY9 chr16 3953387 4116442 - ADD2 chr2 70607618 70768225 - ADI1 chr2 3497366 3519531 - AL513165.2 chr9 37512547 37592469 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-22-3p chr17 1713914 1713935 - hsa-miR-33a-5p chr22 41900949 41900969 + hsa-miR-147a chr9 120244985 120245004 - hsa-miR-377-3p chr14 101062094 101062115 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-33b-5p chr17 17813897 17813916 - hsa-miR-362-3p chrX 50009005 50009026 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC106820.2 chr16 2464950 2468213 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA