exRNAdisease

Entry Detail

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General Information

Database ID: exR0023822 RNA Name: IGF2BP3 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 23310209 End Site(bp): 23470491 External Links: ENSG00000136231

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA1 chr9 104781006 104928155 - AC073508.2 chr17 40627356 40665141 - AC073896.1 chr12 56285916 56316059 - AC135050.2 chr16 31083439 31094956 - AKIRIN1 chr1 38991276 39006059 + AL121594.1 chr14 35122549 35317474 + AL133352.1 chr10 100505628 100529881 - AL365205.1 chr6 41780349 41790141 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-27a-3p chr19 13836447 13836467 - hsa-miR-181a-5p chr1 198859108 198859130 - hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-27b-3p chr9 95085505 95085525 + hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-382-5p chr14 101054316 101054337 + hsa-miR-513a-5p chrX 147213538 147213555 - hsa-miR-320b chr1 224257049 224257070 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021078.1 chr5 149494314 149504670 - AC133644.3 chr2 87455476 87767359 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA