exRNAdisease

Entry Detail

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General Information

Database ID: exR0024186 RNA Name: JARID2 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 15246069 End Site(bp): 15522042 External Links: ENSG00000008083

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.6 chr12 6556886 6607367 - AC010132.3 chr7 42909273 42932174 - AC091959.3 chr5 146203550 146339251 + AFG3L2 chr18 12328944 12377227 - AL162417.1 chr9 133098121 133163914 - AL365205.1 chr6 41780349 41790141 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-147a chr9 120244985 120245004 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-409-3p chr14 101065346 101065367 + hsa-miR-497-5p chr17 7017979 7017999 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC024337.2 chr15 96080713 96084584 - AC133644.3 chr2 87455476 87767359 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA