exRNAdisease

Entry Detail

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General Information

Database ID: exR0024397 RNA Name: KIAA0232 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 6781375 End Site(bp): 6884170 External Links: ENSG00000170871

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADRM1 chr20 62302093 62308862 + ALDH3A2 chr17 19648136 19685760 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-301a-3p chr17 59151149 59151171 - hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-525-5p chr19 53697547 53697567 + hsa-miR-513a-5p chrX 147213538 147213555 - hsa-miR-671-5p chr7 151238449 151238471 + hsa-miR-454-3p chr17 59137787 59137809 - hsa-miR-362-3p chrX 50009005 50009026 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012321.1 chr16 69703065 69704652 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA