Entry Detail



General Information

Database ID:exR0080582
RNA Name:RPL19
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):39200283End Site(bp):39204732
External Links:ENSG00000108298



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
A1BG
chr19
58345178
58353492
-
ABCA1
chr9
104781006
104928155
-
ABCC4
chr13
95019835
95301475
-
ABI2
chr2
203328239
203447728
+
AC018523.2
chr11
14493783
14520344
-
AC073508.2
chr17
40627356
40665141
-
AC084337.2
chr11
6481485
6508978
+
AC134669.1
chr17
31305213
31318831
-
AC245033.1
chr15
82536788
82573194
-
ACACA
chr17
37084992
37406836
-
ACLY
chr17
41866917
41930542
-
ACTG1
chr17
81509971
81523847
-
ADAM10
chr15
58588809
58749791
-
ADGRG6
chr6
142301854
142446266
+
AGO2
chr8
140520156
140635633
-
AHCY
chr20
34280268
34311802
-
AIMP2
chr7
6009255
6023834
+
AL121753.1
chr20
35267885
35280043
-
AL121758.1
chr20
646626
675800
-
AL138752.2
chr9
37588413
38068687
-
AL513165.2
chr9
37512547
37592469
-
ALDH18A1
chr10
95605941
95656711
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006213.1
chr19
43996896
44003298
-
AC012313.3
chr19
58346854
58362751
-
AC023509.1
chr12
53441741
53467528
+
AC113189.2
chr17
7420103
7444081
+
AC113189.4
chr17
7439506
7445966
+
AC245033.4
chr15
82533175
82540008
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA