Entry Detail


General Information

Database ID:exR0093086
RNA Name:hsa-miR-130a-5p
RNA Type:miRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):57641212End Site(bp):57641233
External Links:hsa-miR-130a-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000384
chr12
27867712
27877119
+
hsa_circ_0000711
chr16
68155889
68160513
+
hsa_circ_0000881
chr19
5653125
5654467
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007780.1
chr17
68413623
68524949
+
AC011503.2
chr19
23927788
23929287
+
AC078846.1
chr7
129604548
129611630
-
AC091564.7
chr11
6610883
6616594
-
AC124068.2
chr15
89335053
89336161
+
AC144548.1
chr12
110387463
110445548
-
AL035458.2
chr20
34234840
34281173
-
GAS5
chr1
173858559
173868882
-
MALAT1
chr11
65497688
65506516
+
MCM3AP-AS1
chr21
46229196
46259390
+
NEAT1
chr11
65422774
65445540
+
SNHG16
chr17
76557764
76565348
+
SNHG5
chr6
85650491
85678932
-
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
TYMSOS
chr18
630886
658340
-
XIST
chrX
73820649
73852723
-
Z93241.1
chr22
42615244
42615907
+
ZNF674-AS1
chrX
46545438
46548841
+
ZSCAN16-AS1
chr6
28015122
28137293
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.