Entry Detail


General Information

Database ID:exR0093145
RNA Name:hsa-miR-151a-3p
RNA Type:miRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):140732587End Site(bp):140732607
External Links:hsa-miR-151a-3p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACP1
chr2
264140
278283
+
PCDHA1
chr5
140786136
141012347
+
PCDHA10
chr5
140855883
141012347
+
PCDHA11
chr5
140868183
141012344
+
PCDHA12
chr5
140875302
141012347
+
PCDHA13
chr5
140882124
141012347
+
PCDHA2
chr5
140794852
141012347
+
PCDHA3
chr5
140801028
141012347
+
PCDHA4
chr5
140806929
141012347
+
PCDHA5
chr5
140821604
141012347
+
PCDHA6
chr5
140827958
141012347
+
PCDHA7
chr5
140834248
141012347
+
PCDHA8
chr5
140841187
141012347
+
PCDHA9
chr5
140847463
141012344
+
PCDHAC1
chr5
140926369
141012344
+
PCDHAC2
chr5
140966470
141012347
+
STRBP
chr9
123109500
123268586
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC044784.1
chr10
8970125
8973468
+
AC104794.2
chr2
10083781
10086101
+
AL160006.1
chr1
110058340
110062555
+
SCARNA9
chr11
93721513
93721865
+
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.