Entry Detail


General Information

Database ID:exR0093185
RNA Name:hsa-miR-183-5p
RNA Type:miRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):129774967End Site(bp):129774988
External Links:hsa-miR-183-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CPNE3
chr8
86514435
86561498
+
ENAH
chr1
225486835
225653142
-
GAPDH
chr12
6534512
6538374
+
GNG5
chr1
84498325
84506581
-
MYLIP
chr6
16129086
16148248
+
NCK2
chr2
105744912
105894274
+
NDST1
chr5
150485818
150558211
+
NR4A2
chr2
156324437
156342348
-
PRKAR2A
chr3
48744597
48847874
-
RAB8A
chr19
16111889
16134234
+
RBFOX2
chr22
35738736
36028824
-
RNF169
chr11
74748849
74842413
+
RTL8A
chrX
135050932
135052196
-
RTL8B
chrX
135020513
135022542
-
SIN3A
chr15
75369379
75455842
-
TGOLN2
chr2
85318020
85328296
-
VANGL1
chr1
115641970
115698224
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001164
chr20
45891031
45923523
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC126365.1
chr17
20788071
20789584
+
AL132780.1
chr14
22929607
22956374
+
KCNQ1OT1
chr11
2608328
2699994
-
MIRLET7BHG
chr22
46053869
46113928
+
NEAT1
chr11
65422774
65445540
+
OIP5-AS1
chr15
41283990
41309737
+
SNHG16
chr17
76557764
76565348
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.