Entry Detail


General Information

Database ID:exR0093221
RNA Name:hsa-miR-193a-5p
RNA Type:miRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):31560016End Site(bp):31560037
External Links:hsa-miR-193a-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADD1
chr4
2843857
2930076
+
ANKRD13B
chr17
29589769
29614761
+
APPL2
chr12
105173297
105236203
-
ARHGEF11
chr1
156934840
157045370
-
ATP5F1D
chr19
1241746
1244825
+
CBFA2T3
chr16
88874858
88977207
-
CRTC3
chr15
90529923
90645345
+
E2F1
chr20
33675477
33686385
-
FAM102A
chr9
127940582
127980989
-
LITAF
chr16
11547722
11636381
-
NR1D2
chr3
23945286
23980617
+
SETD1A
chr16
30957754
30984664
+
SLC25A44
chr1
156193932
156212796
+
SPRY4
chr5
142310427
142326455
-
THUMPD1
chr16
20702816
20742084
-
USP21
chr1
161159450
161165723
+
ADSL
chr22
40346500
40390463
+
AL022238.4
chr22
40346529
40410054
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001805
chr8
68015271
68044315
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC239868.1
chr1
149861271
149862504
+
SNHG16
chr17
76557764
76565348
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.