Entry Detail


General Information

Database ID:exR0093236
RNA Name:hsa-miR-198
RNA Type:miRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):120395703End Site(bp):120395724
External Links:hsa-miR-198



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
C18orf25
chr18
46173553
46266992
+
CGN
chr1
151510510
151538692
+
CS
chr12
56271699
56300391
-
FSTL1
chr3
120392293
120450993
-
UBE2K
chr4
39698109
39782792
+
CCDC103
chr17
44899142
44905390
+
CLTC
chr17
59619689
59696956
+
FAM187A
chr17
44899712
44905390
+
LRRC20
chr10
70298970
70382650
-
MAP1B
chr5
72107234
72209565
+
NECTIN2
chr19
44846175
44889223
+
RRP7A
chr22
42508344
42519796
-
TPGS2
chr18
36777647
36829216
-
TUBA1A
chr12
49184795
49189080
-
ZNF281
chr1
200404940
200410056
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
FTX
chrX
73940435
74293574
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.