Entry Detail


General Information

Database ID:exR0093355
RNA Name:hsa-miR-296-5p
RNA Type:miRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):58817661End Site(bp):58817681
External Links:hsa-miR-296-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTN4
chr19
38647649
38731589
+
CBX1
chr17
48070052
48101478
-
EPHB4
chr7
100802565
100827523
-
FOXP4
chr6
41546426
41602384
+
GOSR2
chr17
46923075
46975524
+
RFX1
chr19
13961530
14007039
-
WDR5
chr9
134135365
134159968
+
ZCCHC3
chr20
297570
300321
+
GNL1
chr6
30541377
30557174
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AL132655.2
chr20
58817132
58817725
-
AL355075.4
chr14
20343048
20343685
-
AL356488.2
chr1
109100193
109100619
+
KCNQ1OT1
chr11
2608328
2699994
-
MIR34AHG
chr1
9148011
9198906
-
MIR663AHG
chr20
26167817
26251546
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.