Entry Detail


General Information

Database ID:exR0093539
RNA Name:hsa-miR-326
RNA Type:miRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):75335108End Site(bp):75335127
External Links:hsa-miR-326



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
DOLPP1
chr9
129081111
129090438
+
GOSR2
chr17
46923075
46975524
+
ITGA5
chr12
54395261
54419266
-
MAP4
chr3
47850690
48089272
-
NME4
chr16
396725
410367
+
PAQR4
chr16
2969270
2973484
+
RC3H1
chr1
173931084
174022357
-
REXO1
chr19
1815248
1848483
-
RTL10
chr22
19846138
19854896
-
STX3
chr11
59713456
59805882
+
TSPAN14
chr10
80454166
80533124
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000128
chr1
151139409
151139890
+
hsa_circ_0000384
chr12
27867712
27877119
+
hsa_circ_0001727
chr7
99621041
99621930
+
hsa_circ_0001865
chr9
86292641
86293514
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC144548.1
chr12
110387463
110445548
-
AL355075.4
chr14
20343048
20343685
-
AL359924.1
chr1
237862175
237928321
+
AP000553.1
chr22
21652270
21670237
+
KCNQ1OT1
chr11
2608328
2699994
-
MIRLET7BHG
chr22
46053869
46113928
+
NEAT1
chr11
65422774
65445540
+
SNHG1
chr11
62851984
62855953
-
SNHG3
chr1
28505980
28510892
+
TUG1
chr22
30969245
30979395
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.