Entry Detail


General Information

Database ID:exR0093546
RNA Name:hsa-miR-331-3p
RNA Type:miRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):95308480End Site(bp):95308500
External Links:hsa-miR-331-3p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATXN7L3
chr17
44191805
44200113
-
DAG1
chr3
49468703
49535618
+
ITGA5
chr12
54395261
54419266
-
NACC1
chr19
13116862
13141147
+
NDST1
chr5
150485818
150558211
+
RPUSD1
chr16
784974
788397
-
SDC1
chr2
20200797
20225433
-
SRF
chr6
43171269
43181506
+
TRABD
chr22
50185915
50199598
+
VCP
chr9
35056064
35072627
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001866
chr9
86293355
86297981
-
hsa_circ_0001865
chr9
86292641
86293514
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005332.7
chr17
68188547
68189165
+
AC016876.2
chr17
7581964
7584086
-
H19
chr11
1995176
2001470
-
KCNQ1OT1
chr11
2608328
2699994
-
NEAT1
chr11
65422774
65445540
+
PDCD4-AS1
chr10
110869868
110872233
-
SNHG7
chr9
136721366
136728184
-
VPS9D1-AS1
chr16
89711856
89718165
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.