exRNAdisease

Entry Detail

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General Information

Database ID: exR0093597 RNA Name: hsa-miR-362-3p RNA Type: miRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 50009005 End Site(bp): 50009026 External Links: hsa-miR-362-3p

Disease Information

Disease Name: Benign Ovarian Disease Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D010049 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease

Expression Detail

GEO ID: GSE106817 Description: Integrated extracellular microRNA profiling for ovarian cancer screening Experimental Design: Cancer vs Control Case Disease Type: Benign Ovarian Disease Case Disease SubType: NA Case Sample: Benign Ovarian Disease Control Sample: Non-Cancer Number of Case: 29 Number of Control: 2759 Number of Samples: 2788

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PTPRJ chr11 47980558 48170841 + KIAA0232 chr4 6781375 6884170 + USF2 chr19 35268962 35279821 + BLCAP chr20 37492472 37527931 - AC009133.6 chr16 29812261 29820092 + WDR82 chr3 52254434 52288020 - PIP4K2B chr17 38765689 38800126 - ARF3 chr12 48935723 48957487 - TRPS1 chr8 115408496 115809673 - UBTF chr17 44205033 44221626 - FAM126B chr2 200973718 201071671 - ZBTB2 chr6 151364115 151391559 - TNFRSF21 chr6 47231532 47309905 - RUNX1 chr21 34787801 36004667 - MTPN chr7 135926760 135977359 - SERTAD3 chr19 40440844 40444335 - DCBLD2 chr3 98795941 98901695 - ATP8B1 chr18 57646426 57803315 - SLF2 chr10 100912963 100965134 + SDCBP chr8 58552924 58582859 + TNFRSF1B chr1 12166991 12209228 + COQ8A chr1 226897536 226987545 + DNAJB9 chr7 108569867 108574850 + VAMP2 chr17 8159149 8163546 - SIK1B chr21 6111131 6123778 + SMAP2 chr1 40344850 40423326 + FAM219A chr9 34398184 34458570 - CA12 chr15 63321378 63381846 - CALM1 chr14 90396502 90408268 + AKAP11 chr13 42272152 42323261 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001588 chr6 26204839 26205043 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - KCNQ1OT1 chr11 2608328 2699994 - MIR663AHG chr20 26167817 26251546 - NEAT1 chr11 65422774 65445540 + SCARNA9 chr11 93721513 93721865 + SNHG25 chr17 64145970 64146476 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE106817 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2535 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30333487 Title: Integrated extracellular microRNA profiling for ovarian cancer screening Author: Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T Journal: Nat Commun. 2018 Oct 17;9(1):4319. Description: to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.