Entry Detail


General Information

Database ID:exR0093613
RNA Name:hsa-miR-3652
RNA Type:miRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):103930425End Site(bp):103930442
External Links:hsa-miR-3652



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATP5MC3
chr2
175176258
175184607
-
GANAB
chr11
62624826
62646726
-
HDLBP
chr2
241227264
241317061
-
PGRMC1
chrX
119236245
119244466
+
PTMA
chr2
231706895
231713541
+
RAB15
chr14
64945814
64973226
-
AC099811.2
chr17
42119674
42154916
-
AP2A1
chr19
49766968
49807113
+
AP2M1
chr3
184174689
184184091
+
ARHGAP33
chr19
35774532
35788822
+
BDNF
chr11
27654893
27722058
-
BRI3
chr7
98252379
98310441
+
CCT6A
chr7
56051685
56063989
+
FKBP8
chr19
18531751
18544077
-
GATC
chr12
120446444
120463749
+
GDF11
chr12
55743122
55757264
+
HLA-DRA
chr6
32439878
32445046
+
HSP90B1
chr12
103930107
103953645
+
MIB2
chr1
1615415
1630610
+
RAB5C
chr17
42124976
42155044
-
SF3A2
chr19
2236824
2248655
+
SFPQ
chr1
35176378
35193145
-
WASF1
chr6
110099819
110180004
-
WBP11
chr12
14784582
14803486
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022819.1
chr15
99157231
99161140
-
AL591742.2
chr1
114032393
114034511
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.