Entry Detail


General Information

Database ID:exR0093716
RNA Name:hsa-miR-382-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101054316End Site(bp):101054337
External Links:hsa-miR-382-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
APCDD1
chr18
10454635
10489949
+
BCAS2
chr1
114567557
114581629
-
BCL2L11
chr2
111119378
111168445
+
CAMTA1
chr1
6785454
7769706
+
COBLL1
chr2
164653624
164843679
-
ELK1
chrX
47635521
47650604
-
FOSL1
chr11
65892049
65900573
-
IGF2BP3
chr7
23310209
23470491
-
KMT5A
chr12
123383773
123409353
+
MAPRE2
chr18
34976928
35143470
+
NID1
chr1
235975830
236065109
-
PARM1
chr4
74933095
75050115
+
PDE8A
chr15
84980440
85139145
+
RAB18
chr10
27504174
27542237
+
SCAF11
chr12
45919131
45992120
-
SH3GL1
chr19
4360370
4400547
-
STEAP3
chr2
119223831
119265652
+
STK40
chr1
36339624
36385896
-
TAGLN
chr11
117199370
117207464
+
TUB
chr11
8019244
8106112
+
UBN2
chr7
139230356
139308236
+
WDR4
chr21
42843094
42879568
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC092718.4
chr16
81030770
81031485
+
AC126365.1
chr17
20788071
20789584
+
FGD5-AS1
chr3
14920347
14948424
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.