exRNAdisease

Entry Detail

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General Information

Database ID: exR0093773 RNA Name: hsa-miR-409-3p RNA Type: miRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 101065346 End Site(bp): 101065367 External Links: hsa-miR-409-3p

Disease Information

Disease Name: Benign Ovarian Disease Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D010049 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease

Expression Detail

GEO ID: GSE106817 Description: Integrated extracellular microRNA profiling for ovarian cancer screening Experimental Design: Cancer vs Control Case Disease Type: Benign Ovarian Disease Case Disease SubType: NA Case Sample: Benign Ovarian Disease Control Sample: Non-Cancer Number of Case: 29 Number of Control: 2759 Number of Samples: 2788

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AP1S1 chr7 101154456 101161596 + JARID2 chr6 15246069 15522042 + SRSF6 chr20 43457893 43466046 + TMEM30A chr6 75252924 75284948 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000816 chr17 80521229 80526077 + hsa_circ_0000418 chr12 69983264 69985939 + hsa_circ_0000943 chr19 47421744 47440665 + hsa_circ_0001085 chr2 191765289 191789319 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC00476 chr9 95759231 95876049 - LINC00630 chrX 102769158 102885406 + NEAT1 chr11 65422774 65445540 + SNHG1 chr11 62851984 62855953 - TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: GSE106817 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2535 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30333487 Title: Integrated extracellular microRNA profiling for ovarian cancer screening Author: Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T Journal: Nat Commun. 2018 Oct 17;9(1):4319. Description: to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.