Entry Detail


General Information

Database ID:exR0094402
RNA Name:hsa-miR-5094
RNA Type:miRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):89850690End Site(bp):89850711
External Links:hsa-miR-5094



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZNHIT3
chr17
36486629
36499310
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001454
chr4
154524454
154533552
+
hsa_circ_0001005
chr2
53921020
53978078
-
hsa_circ_0000384
chr12
27867712
27877119
+
hsa_circ_0001159
chr20
40161688
40179999
-
hsa_circ_0000698
chr16
47531309
47549512
+
hsa_circ_0001445
chr4
144464661
144465125
+
hsa_circ_0000943
chr19
47421744
47440665
+
hsa_circ_0001667
chr7
810107
814799
+
hsa_circ_0001376
chr3
194169185
194175121
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC074117.1
chr2
27356246
27367622
+
AL356488.2
chr1
109100193
109100619
+
AL359091.1
chr9
128392007
128393510
-
DSCAM-AS1
chr21
40383083
40385358
+
FTX
chrX
73940435
74293574
-
GAS5
chr1
173858559
173868882
-
NEAT1
chr11
65422774
65445540
+
NUTM2B-AS1
chr10
79661394
79826594
-
PDCD4-AS1
chr10
110869868
110872233
-
SNHG3
chr1
28505980
28510892
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.