Entry Detail


General Information

Database ID:exR0094405
RNA Name:hsa-miR-5100
RNA Type:miRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):42997630End Site(bp):42997651
External Links:hsa-miR-5100



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SNU13
chr22
41673933
41690504
-
GHITM
chr10
84139509
84153568
+
AGRN
chr1
1020120
1056118
+
PRRC2B
chr9
131373636
131500197
+
HNRNPH1
chr5
179614178
179634784
-
GTF3C4
chr9
132670035
132694953
+
PPCDC
chr15
75023586
75117462
+
SLC35B1
chr17
49700934
49709014
-
SRP72
chr4
56467617
56503681
+
SRPK1
chr6
35832966
35921342
-
CHPF
chr2
219538948
219543809
-
NOP14
chr4
2937933
2963406
-
SLC52A2
chr8
144354135
144361272
+
THOP1
chr19
2785503
2815807
+
MACF1
chr1
39081316
39487177
+
CPTP
chr1
1324756
1328896
+
UBR4
chr1
19074510
19210266
-
ZNF136
chr19
12163064
12189871
+
HCN1
chr5
45254948
45696498
-
NUP93
chr16
56730118
56850286
+
KCTD2
chr17
75032575
75065889
+
NIN
chr14
50719763
50831121
-
KDSR
chr18
63327726
63367228
-
ATP1A1
chr1
116372668
116410261
+
PRMT6
chr1
107056674
107067636
+
FLNA
chrX
154348524
154374638
-
NUP107
chr12
68686951
68745809
+
P4HTM
chr3
48989889
49007153
+
VSIG10
chr12
118063593
118136026
-
WASF2
chr1
27404230
27490167
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
POLR2J4
chr7
43940895
44019175
-
SNHG3
chr1
28505980
28510892
+
AC008738.2
chr19
33305036
33309387
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.