Entry Detail


General Information

Database ID:exR0094421
RNA Name:hsa-miR-515-5p
RNA Type:miRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):53685022End Site(bp):53685045
External Links:hsa-miR-515-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CSNK2A1
chr20
472498
543835
-
HCFC1
chrX
153947557
153971818
-
HTD2
chr3
58306262
58318574
+
NR3C1
chr5
143277931
143435512
-
PACS1
chr11
66070272
66244744
+
RPP14
chr3
58306247
58324695
+
SLC31A1
chr9
113221544
113264492
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001349
chr3
152132729
152150709
+
hsa_circ_0001409
chr4
48835417
48859382
+
hsa_circ_0000987
chr2
30748452
30756180
+
hsa_circ_0000670
chr16
9199043
9199243
+
hsa_circ_0001495
chr5
68470703
68471364
+
hsa_circ_0001329
chr3
119219541
119222868
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007780.1
chr17
68413623
68524949
+
AC021078.1
chr5
149494314
149504670
-
ENTPD3-AS1
chr3
40313802
40453329
-
GAS5
chr1
173858559
173868882
-
KCNQ1OT1
chr11
2608328
2699994
-
LINC01578
chr15
92819540
92899701
+
MALAT1
chr11
65497688
65506516
+
SNHG3
chr1
28505980
28510892
+
TUG1
chr22
30969245
30979395
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.