Entry Detail


General Information

Database ID:exR0094759
RNA Name:hsa-miR-620
RNA Type:miRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):116148575End Site(bp):116148594
External Links:hsa-miR-620



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BACH1
chr21
29194071
29630751
+
CDC37
chr19
10391133
10420121
-
CTDSP2
chr12
57819927
57846729
-
FAM13B
chr5
137937960
138051961
-
IGFBP4
chr17
40443450
40457725
+
IRF2BP2
chr1
234604269
234609525
-
PATL1
chr11
59636716
59669037
-
PCDH10
chr4
133149294
133208606
+
RCC2
chr1
17406760
17439677
-
SLC29A1
chr6
44219553
44234142
+
ZNF587
chr19
57849859
57865117
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001247
chr22
46125304
46136418
+
hsa_circ_0001159
chr20
40161688
40179999
-
hsa_circ_0000471
chr13
33091993
33101669
-
hsa_circ_0001666
chr6
170626457
170639638
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC239868.1
chr1
149861271
149862504
+
AC245033.4
chr15
82533175
82540008
-
AP000233.2
chr21
25095022
25103670
+
MALAT1
chr11
65497688
65506516
+
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
NR2F2-AS1
chr15
96110040
96327361
-
OIP5-AS1
chr15
41283990
41309737
+
SNHG12
chr1
28578538
28583132
-
SNHG8
chr4
118278709
118285316
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.