Entry Detail


General Information

Database ID:exR0094773
RNA Name:hsa-miR-629-5p
RNA Type:miRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):70079427End Site(bp):70079447
External Links:hsa-miR-629-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BAZ2A
chr12
56595596
56636816
-
CBX2
chr17
79778148
79787983
+
CBX3
chr7
26201162
26213607
+
COL4A1
chr13
110148963
110307157
-
DENND5B
chr12
31382226
31591136
-
GRB10
chr7
50590063
50793462
-
HDLBP
chr2
241227264
241317061
-
LDLR
chr19
11089462
11133820
+
MCM3
chr6
52264014
52284881
-
MSI1
chr12
120341330
120369164
-
NOLC1
chr10
102152176
102163871
+
PA2G4
chr12
56104537
56113910
+
PHF12
chr17
28905250
28951771
-
PRR12
chr19
49591182
49626439
+
RSU1
chr10
16590611
16817463
-
SH3KBP1
chrX
19533977
19887600
-
SH3PXD2A
chr10
103594027
103855543
-
TULP4
chr6
158232236
158511828
+
UBN2
chr7
139230356
139308236
+
WIPF2
chr17
40219304
40284136
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000384
chr12
27867712
27877119
+
hsa_circ_0001230
chr22
38895404
38897285
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC021078.1
chr5
149494314
149504670
-
NEAT1
chr11
65422774
65445540
+
U62317.3
chr22
50597152
50597599
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.