Entry Detail


General Information

Database ID:exR0094787
RNA Name:hsa-miR-642a-5p
RNA Type:miRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):45674943End Site(bp):45674964
External Links:hsa-miR-642a-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AFF4
chr5
132875395
132963634
-
ARID3A
chr19
925781
975939
+
E2F3
chr6
20401879
20493714
+
GFOD1
chr6
13357830
13487662
-
HIF1AN
chr10
100529072
100559998
+
MAP3K12
chr12
53479669
53500063
-
MAPKAPK2
chr1
206684944
206734283
+
MDK
chr11
46380756
46383837
+
PPP6R1
chr19
55229779
55259017
-
SIK2
chr11
111602449
111730855
+
SLC7A2
chr8
17497088
17570573
+
SYVN1
chr11
65121780
65134533
-
TMED10
chr14
75131469
75176612
-
TMEM30B
chr14
61277370
61281761
-
UBR3
chr2
169827454
170084131
+
VAT1
chr17
43014607
43025123
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001005
chr2
53921020
53978078
-
hsa_circ_0001146
chr20
34241449
34246936
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004832.5
chr22
30420512
30420912
+
AC007952.4
chr17
19112000
19112636
-
AC010327.5
chr19
55216660
55221616
+
AC016876.2
chr17
7581964
7584086
-
AL645465.1
chr1
244375100
244409592
-
MIR34AHG
chr1
9148011
9198906
-
MIR497HG
chr17
7015818
7019659
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
ZFAS1
chr20
49278178
49299600
+
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.