exRNAdisease

Entry Detail

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General Information

Database ID: exR0095115 RNA Name: hsa-miR-6838-5p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 44073407 End Site(bp): 44073428 External Links: hsa-miR-6838-5p

Disease Information

Disease Name: Benign Ovarian Disease Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D010049 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease

Expression Detail

GEO ID: GSE106817 Description: Integrated extracellular microRNA profiling for ovarian cancer screening Experimental Design: Cancer vs Control Case Disease Type: Benign Ovarian Disease Case Disease SubType: NA Case Sample: Benign Ovarian Disease Control Sample: Non-Cancer Number of Case: 29 Number of Control: 2759 Number of Samples: 2788

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0001005 chr2 53921020 53978078 - hsa_circ_0001723 chr7 91924202 91948826 + hsa_circ_0000458 chr12 124071293 124074996 + hsa_circ_0001699 chr7 40027197 40041630 + hsa_circ_0001387 chr4 1902352 1936989 + hsa_circ_0001168 chr20 47691321 47707559 + hsa_circ_0000552 chr14 71880664 71948928 + hsa_circ_0000038 chr1 28800065 28802803 + hsa_circ_0000652 chr15 90984737 90986710 + hsa_circ_0001472 chr5 36953719 36976504 + hsa_circ_0001263 chr3 5215701 5216099 + hsa_circ_0000799 chr17 65941524 65972074 + hsa_circ_0001164 chr20 45891031 45923523 - hsa_circ_0000032 chr1 25666964 25669564 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC003092.1 chr7 94022833 94066661 + NUTM2B-AS1 chr10 79661394 79826594 - LINC02035 chr3 122886941 122892416 + AL031282.2 chr1 1702736 1737688 - AC009022.1 chr16 69976297 70065948 - AC020978.7 chr16 68224713 68227734 + MIR29B2CHG chr1 207801518 207879115 - AC002470.2 chr22 20979462 20998121 + LINC01184 chr5 127939152 128083172 - SNHG12 chr1 28578538 28583132 - XIST chrX 73820649 73852723 - AC021078.1 chr5 149494314 149504670 - AC021092.1 chr19 44103007 44113183 - AL359924.1 chr1 237862175 237928321 + MIR497HG chr17 7015818 7019659 - HCG18 chr6 30286690 30327382 - LINC00649 chr21 33915534 33977691 + SNHG25 chr17 64145970 64146476 + AC079781.5 chr7 97851688 97972985 - AP000317.2 chr21 34073592 34360033 + AC114980.1 chr5 93860669 93863825 - NEAT1 chr11 65422774 65445540 + SNHG16 chr17 76557764 76565348 + LINC00662 chr19 27681072 27794005 - MIR503HG chrX 134543119 134546642 - STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + AL391244.1 chr1 1420245 1422691 + SNHG1 chr11 62851984 62855953 - MCM3AP-AS1 chr21 46229196 46259390 + MZF1-AS1 chr19 58559129 58574797 + Display:

Experiment Detail

GEO ID: GSE106817 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2535 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30333487 Title: Integrated extracellular microRNA profiling for ovarian cancer screening Author: Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T Journal: Nat Commun. 2018 Oct 17;9(1):4319. Description: to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.