Entry Detail


General Information

Database ID:exR0095297
RNA Name:hsa-miR-7705
RNA Type:miRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):100703002End Site(bp):100703024
External Links:hsa-miR-7705



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CTNND1
chr11
57753243
57819546
+
FSTL1
chr3
120392293
120450993
-
CTNNA1
chr5
138610967
138935034
+
EIF3H
chr8
116642130
116766925
-
MLF1
chr3
158571163
158607252
+
NTPCR
chr1
232950605
232983882
+
PABPC1
chr8
100685816
100722809
-
PABPC3
chr13
25095868
25099254
+
RPL27
chr17
42998273
43002959
+
RPLP2
chr11
809965
812880
+
RPP30
chr10
90871716
90908553
+
RPS6
chr9
19375715
19380236
-
SRSF1
chr17
58000919
58007346
-
TTYH2
chr17
74213571
74262020
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.