Entry Detail


General Information

Database ID:exR0095447
RNA Name:hsa-miR-101-3p
RNA Type:miRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):65058442End Site(bp):65058462
External Links:hsa-miR-101-3p



Disease Information

Disease Name:Borderline Ovarian Tumor
Disease Category:Cancers
MeSH ID:D010051
Type:Neoplasms/Urogenital Neoplasms
Alias:Ovarian Neoplasms//Neoplasm, Ovarian//Ovarian Neoplasm//Ovary Neoplasms//Neoplasm, Ovary//Neoplasms, Ovary//Ovary Neoplasm//Neoplasms, Ovarian//Ovary Cancer//Cancer, Ovary//Cancers, Ovary//Ovary Cancers//Ovarian Cancer//Cancer, Ovarian//Cancers, Ovarian//Ovarian Cancers//Cancer of Ovary//Cancer of the Ovary



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Borderline Ovarian Tumor
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AEN
chr15
88621337
88632281
+
CA12
chr15
63321378
63381846
-
CNOT11
chr2
101252886
101270316
+
CPEB2
chr4
15002674
15070153
+
DIP2B
chr12
50504985
50748657
+
GABPB1
chr15
50275392
50355408
-
JUNB
chr19
12791486
12793315
+
PLS1
chr3
142596393
142713664
+
USP47
chr11
11841423
11961887
+
WDCP
chr2
24029347
24049575
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC024940.6
chr12
31280422
31280895
-
AC145207.5
chr17
81878425
81881106
-
AC243964.3
chr19
44631573
44725217
-
AC245297.2
chr1
149264252
149264816
+
EBLN3P
chr9
37079645
37090928
+
MALAT1
chr11
65497688
65506516
+
NEAT1
chr11
65422774
65445540
+
SNHG1
chr11
62851984
62855953
-
SNHG6
chr8
66921684
66926398
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.