Entry Detail


General Information

Database ID:exR0097422
RNA Name:hsa-miR-6728-3p
RNA Type:miRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):8866502End Site(bp):8866522
External Links:hsa-miR-6728-3p



Disease Information

Disease Name:Borderline Ovarian Tumor
Disease Category:Cancers
MeSH ID:D010051
Type:Neoplasms/Urogenital Neoplasms
Alias:Ovarian Neoplasms//Neoplasm, Ovarian//Ovarian Neoplasm//Ovary Neoplasms//Neoplasm, Ovary//Neoplasms, Ovary//Ovary Neoplasm//Neoplasms, Ovarian//Ovary Cancer//Cancer, Ovary//Cancers, Ovary//Ovary Cancers//Ovarian Cancer//Cancer, Ovarian//Cancers, Ovarian//Ovarian Cancers//Cancer of Ovary//Cancer of the Ovary



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Borderline Ovarian Tumor
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EDARADD
chr1
236348257
236502915
+
ENO1
chr1
8861000
8879190
-
ENO3
chr17
4948092
4957131
+
MT-ND4
chrMT
10760
12137
+
RPS3
chr11
75399515
75422280
+
SET
chr9
128683424
128696400
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.