Entry Detail


General Information

Database ID:exR0153084
RNA Name:hsa-miR-101-3p
RNA Type:miRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):65058442End Site(bp):65058462
External Links:hsa-miR-101-3p



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE113234
Description:Circulating microRNAs combined with PSA for an accurate and non-invasive prostate cancer detection
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:NA
Case Sample:Prostate Cancer
Control Sample:Healthy
Number of Case:60
Number of Control:27
Number of Samples:87





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AEN
chr15
88621337
88632281
+
CA12
chr15
63321378
63381846
-
CNOT11
chr2
101252886
101270316
+
CPEB2
chr4
15002674
15070153
+
DIP2B
chr12
50504985
50748657
+
GABPB1
chr15
50275392
50355408
-
JUNB
chr19
12791486
12793315
+
PLS1
chr3
142596393
142713664
+
USP47
chr11
11841423
11961887
+
WDCP
chr2
24029347
24049575
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC024940.6
chr12
31280422
31280895
-
AC145207.5
chr17
81878425
81881106
-
AC243964.3
chr19
44631573
44725217
-
AC245297.2
chr1
149264252
149264816
+
EBLN3P
chr9
37079645
37090928
+
MALAT1
chr11
65497688
65506516
+
NEAT1
chr11
65422774
65445540
+
SNHG1
chr11
62851984
62855953
-
SNHG6
chr8
66921684
66926398
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE113234
Sample Source:Blood
Source Fraction:Plasma
Platform:GPL19730
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1972
Sample treatment protocol:NA
RNA Extract protocol:Extraction was performed using miRNEasy serum/plasma kit from Qiagen.
RNA library preparation protocol:Briefly, 4 ul of totRNA were dephosphorylated and denaturated; then a ligation and labeling step with Cy3 was performed



Reference

PMID:30452625
Title:Circulating microRNAs combined with PSA for accurate and non-invasive prostate cancer detection
Author:Mello-Grand M, Gregnanin I, Sacchetto L, Ostano P, Zitella A, Bottoni G, Oderda M, Marra G, Munegato S, Pardini B, Naccarati A, Gasparini M, Gontero P, Chiorino G
Journal:Carcinogenesis. 2019 Apr 29;40(2):246-253.
Description:we propose to combine circulating microRNAs (miRs) with PSA, to improve the diagnostic route for PCa