exRNAdisease

Entry Detail

---



General Information

Database ID: exR0153284 RNA Name: hsa-miR-147b-3p RNA Type: miRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 45433098 End Site(bp): 45433118 External Links: hsa-miR-147b-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE113234 Description: Circulating microRNAs combined with PSA for an accurate and non-invasive prostate cancer detection Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: NA Case Sample: Prostate Cancer Control Sample: Healthy Number of Case: 60 Number of Control: 27 Number of Samples: 87

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADCY9 chr16 3953387 4116442 - FASN chr17 82078338 82098294 - FGFRL1 chr4 1009936 1026898 + IGF2 chr11 2129112 2141238 - MGRN1 chr16 4616493 4690974 + MNT chr17 2384073 2401104 - PRDX2 chr19 12796820 12801800 - SDC4 chr20 45325288 45348424 - TNPO3 chr7 128954180 129055173 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE113234 Sample Source: Blood Source Fraction: Plasma Platform: GPL19730 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1972 Sample treatment protocol: NA RNA Extract protocol: Extraction was performed using miRNEasy serum/plasma kit from Qiagen. RNA library preparation protocol: Briefly, 4 ul of totRNA were dephosphorylated and denaturated; then a ligation and labeling step with Cy3 was performed

Reference

PMID: 30452625 Title: Circulating microRNAs combined with PSA for accurate and non-invasive prostate cancer detection Author: Mello-Grand M, Gregnanin I, Sacchetto L, Ostano P, Zitella A, Bottoni G, Oderda M, Marra G, Munegato S, Pardini B, Naccarati A, Gasparini M, Gontero P, Chiorino G Journal: Carcinogenesis. 2019 Apr 29;40(2):246-253. Description: we propose to combine circulating microRNAs (miRs) with PSA, to improve the diagnostic route for PCa