exRNAdisease

Entry Detail

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General Information

Database ID: exR0153603 RNA Name: hsa-miR-3163 RNA Type: miRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 66934476 End Site(bp): 66934497 External Links: hsa-miR-3163

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE113234 Description: Circulating microRNAs combined with PSA for an accurate and non-invasive prostate cancer detection Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: NA Case Sample: Prostate Cancer Control Sample: Healthy Number of Case: 60 Number of Control: 27 Number of Samples: 87

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000642 chr15 80390757 80415142 + hsa_circ_0000643 chr15 80412669 80415142 + hsa_circ_0001414 chr4 56277780 56284152 + hsa_circ_0000106 chr1 111690263 111703918 + hsa_circ_0000552 chr14 71880664 71948928 + hsa_circ_0000799 chr17 65941524 65972074 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007038.1 chr2 210028417 210029156 + AC010980.2 chr2 222317242 222318653 - AC021078.1 chr5 149494314 149504670 - AC022167.2 chr16 8848105 8860456 + AC051619.7 chr15 45200325 45200632 - AC092718.4 chr16 81030770 81031485 + AC243964.3 chr19 44631573 44725217 - DLEU2 chr13 49956670 50125720 - DSCAM-AS1 chr21 40383083 40385358 + FGD5-AS1 chr3 14920347 14948424 - GABPB1-AS1 chr15 50354959 50372202 + HCG11 chr6 26521709 26527404 + LINC00662 chr19 27681072 27794005 - MALAT1 chr11 65497688 65506516 + MEG8 chr14 100894770 101038859 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - SNHG1 chr11 62851984 62855953 - SNHG5 chr6 85650491 85678932 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE113234 Sample Source: Blood Source Fraction: Plasma Platform: GPL19730 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1972 Sample treatment protocol: NA RNA Extract protocol: Extraction was performed using miRNEasy serum/plasma kit from Qiagen. RNA library preparation protocol: Briefly, 4 ul of totRNA were dephosphorylated and denaturated; then a ligation and labeling step with Cy3 was performed

Reference

PMID: 30452625 Title: Circulating microRNAs combined with PSA for accurate and non-invasive prostate cancer detection Author: Mello-Grand M, Gregnanin I, Sacchetto L, Ostano P, Zitella A, Bottoni G, Oderda M, Marra G, Munegato S, Pardini B, Naccarati A, Gasparini M, Gontero P, Chiorino G Journal: Carcinogenesis. 2019 Apr 29;40(2):246-253. Description: we propose to combine circulating microRNAs (miRs) with PSA, to improve the diagnostic route for PCa