exRNAdisease

Entry Detail

General Information

Database ID:

exR0196202

RNA Name:

hsa-miR-1181

RNA Type:

miRNA

Chromosome:

chr19

Starnd:

-

Coordinate:

Start Site(bp):

10403505

End Site(bp):

10403525

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CDC37	chr19	10391133	10420121	-
CHD7	chr8	60678740	60868028	+
IRS2	chr13	109752695	109786583	-
MAZ	chr16	29806106	29811164	+
PIM1	chr6	37170152	37175428	+
RRP1B	chr21	43659560	43696079	+
ZMIZ1	chr10	79068966	79316528	+
CAMK4	chr5	111223653	111494886	+
ELF1	chr13	40931924	41061440	-
GNAS	chr20	58839718	58911192	+
GSPT1	chr16	11868128	11916082	-
HNRNPA0	chr5	137745651	137754363	-
HNRNPUL2	chr11	62712630	62727457	-
HNRNPUL2-BSCL2	chr11	62690275	62727384	-
IMMT	chr2	86143932	86195770	-
MDFIC	chr7	114922154	115019202	+
PRKAA2	chr1	56645314	56715335	+
RAB21	chr12	71754863	71800286	+
RALY	chr20	33993646	34108308	+
SLC4A4	chr4	71062667	71572087	+
SOX1	chr13	112067149	112071706	+
SPINT2	chr19	38244035	38292615	+
TMEFF1	chr9	100473149	100577636	+
TTC3	chr21	37073226	37203112	+
U2AF1	chr21	43092956	43107587	-
U2AF1L5	chr21	6484623	6499261	-
UBE2D2	chr5	139526431	139628434	+
ZNF282	chr7	149195546	149226238	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007216.1	chr16	11976851	11977850	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia