exRNAdisease

Entry Detail

General Information

Database ID:

exR0196280

RNA Name:

hsa-miR-126-5p

RNA Type:

miRNA

Chromosome:

chr9

Starnd:

+

Coordinate:

Start Site(bp):

136670616

End Site(bp):

136670636

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

NA

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001731	chr7	100731990	100738448	+
hsa_circ_0000598	chr15	45009906	45009989	+
hsa_circ_0000943	chr19	47421744	47440665	+
hsa_circ_0001146	chr20	34241449	34246936	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC009032.1	chr16	69632141	69632571	+
AC010655.4	chr7	128455840	128493859	+
AC078846.1	chr7	129604548	129611630	-
AC124798.1	chr11	17380649	17383531	+
FGD5-AS1	chr3	14920347	14948424	-
HOTAIR	chr12	53962308	53974956	-
LINC00667	chr18	5237826	5290608	+
LINC00943	chr12	126723412	126749027	+
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
NUTM2B-AS1	chr10	79661394	79826594	-
OIP5-AS1	chr15	41283990	41309737	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia