exRNAdisease

Entry Detail

General Information

Database ID:

exR0196332

RNA Name:

hsa-miR-1294

RNA Type:

miRNA

Chromosome:

chr5

Starnd:

+

Coordinate:

Start Site(bp):

154347153

End Site(bp):

154347174

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CYB5R3	chr22	42617840	42649392	-
STK40	chr1	36339624	36385896	-
EIF4A1	chr17	7572706	7579006	+
TRAPPC10	chr21	44012309	44106552	+
ABCA1	chr9	104781006	104928155	-
POGK	chr1	166839447	166856344	+
FGFR1	chr8	38400215	38468834	-
KMT2A	chr11	118436490	118526832	+
RAB8A	chr19	16111889	16134234	+
TEX261	chr2	70985942	70994873	-
ANKRD49	chr11	94493979	94499578	+
PGRMC1	chrX	119236245	119244466	+
PTMS	chr12	6765516	6770952	+
CRY2	chr11	45847118	45883248	+
PTP4A1	chr6	63521746	63583436	+
APLP2	chr11	130068147	130144811	+
CDKN1B	chr12	12715058	12722369	+
UBE2G2	chr21	44768580	44801826	-
PDPR	chr16	70113626	70162537	+
AKT2	chr19	40230317	40285536	-
RNF157	chr17	76142465	76240493	-
ZHX3	chr20	41178448	41317672	-
ARHGAP28	chr18	6729718	6915716	+
PRRC2B	chr9	131373636	131500197	+
FYCO1	chr3	45917899	45995824	-
ZNF512B	chr20	63956704	63969930	-
SMAD7	chr18	48919853	48952052	-
PDE4DIP	chr1	148808181	149048286	+
TAGLN2	chr1	159918107	159925732	-
NACC1	chr19	13116862	13141147	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000247	chr10	74474868	74475660	+
hsa_circ_0000798	chr17	65941524	65944422	+
hsa_circ_0000246	chr10	74468040	74475660	+
hsa_circ_0001085	chr2	191765289	191789319	+
hsa_circ_0000744	chr17	15968183	15971435	-
hsa_circ_0000799	chr17	65941524	65972074	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007161.3	chr7	7640752	8004053	+
AC021078.1	chr5	149494314	149504670	-
AC022150.4	chr19	52650437	52653284	-
AL022311.1	chr22	37876148	37895563	+
H19	chr11	1995176	2001470	-
LINC00265	chr7	39733430	39793092	+
NEAT1	chr11	65422774	65445540	+
TUG1	chr22	30969245	30979395	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia