exRNAdisease

Entry Detail

General Information

Database ID:

exR0196381

RNA Name:

hsa-miR-139-5p

RNA Type:

miRNA

Chromosome:

chr11

Starnd:

-

Coordinate:

Start Site(bp):

72615102

End Site(bp):

72615124

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AP3M1	chr10	74120255	74151063	-
ARIH1	chr15	72474330	72602987	+
FBN2	chr5	128257909	128659185	-
ISG20L2	chr1	156721891	156728799	-
ITGA3	chr17	50055968	50090481	+
JPT2	chr16	1678256	1702280	+
KLHL28	chr14	44924319	45042322	-
LRP8	chr1	53242364	53328469	-
MKLN1	chr7	131110096	131496632	+
SLC26A2	chr5	149960758	149993455	+
SLC31A1	chr9	113221544	113264492	+
TGOLN2	chr2	85318020	85328296	-
TPM4	chr19	16067021	16103002	+
WIPF2	chr17	40219304	40284136	+
YWHAB	chr20	44885702	44908532	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC068768.1	chr12	123262060	123262402	+
AC084082.1	chr8	66112667	66126632	+
AL132655.1	chr20	58833809	58836529	-
NEAT1	chr11	65422774	65445540	+
NUTM2A-AS1	chr10	87201647	87342612	-
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia