exRNAdisease

Entry Detail

General Information

Database ID:

exR0196383

RNA Name:

hsa-miR-140-5p

RNA Type:

miRNA

Chromosome:

chr16

Starnd:

+

Coordinate:

Start Site(bp):

69933103

End Site(bp):

69933124

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ARIH1	chr15	72474330	72602987	+
BTBD7	chr14	93237550	93333092	-
C15orf41	chr15	36579626	36810248	+
CLPTM1	chr19	44954585	44993341	+
COL4A2	chr13	110305812	110513209	+
ITPRIPL2	chr16	19113932	19121629	+
NME4	chr16	396725	410367	+
POLR3G	chr5	90471748	90514557	+
SCRN1	chr7	29920104	29990289	-
SLC6A6	chr3	14402576	14489349	+
SRP14	chr15	40035690	40039181	-
TMEM181	chr6	158536436	158635428	+
TNRC6B	chr22	40044817	40335808	+
TRIO	chr5	14143342	14532128	+
ZNF800	chr7	127346790	127431924	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000712	chr16	68208276	68225678	+
hsa_circ_0001699	chr7	40027197	40041630	+
hsa_circ_0001472	chr5	36953719	36976504	+
hsa_circ_0000032	chr1	25666964	25669564	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AL162258.1	chr1	153626332	153634340	-
DHRS4-AS1	chr14	23938219	24052555	-
H19	chr11	1995176	2001470	-
KCNQ1OT1	chr11	2608328	2699994	-
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
SNHG1	chr11	62851984	62855953	-
SNHG16	chr17	76557764	76565348	+
SNHG20	chr17	77086716	77099902	+
TDRKH-AS1	chr1	151790804	151794402	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia