exRNAdisease

Entry Detail

General Information

Database ID:

exR0196386

RNA Name:

hsa-miR-142-3p

RNA Type:

miRNA

Chromosome:

chr17

Starnd:

-

Coordinate:

Start Site(bp):

58331245

End Site(bp):

58331267

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
BLOC1S6	chr15	45587214	45615945	+
BOD1	chr5	173607145	173616659	-
CUL5	chr11	108008898	108107761	+
ETFRF1	chr12	25195216	25209645	+
SEMA7A	chr15	74409289	74433958	-
TNRC6B	chr22	40044817	40335808	+
ZNF676	chr19	22179089	22215801	-
AL139011.2	chr1	160216800	160285130	-
B2M	chr15	44711487	44718877	+
CCDC126	chr7	23597382	23644708	+
EEF1A1	chr6	73515750	73523797	-
MAST2	chr1	45786987	46036122	+
MBD3	chr19	1573596	1592865	-
MRPL18	chr6	159789812	159798436	+
NDUFA2	chr5	140638740	140647785	-
PEX19	chr1	160276812	160286348	-
PRDX1	chr1	45511036	45523047	-
RPL27	chr17	42998273	43002959	+
SLC35F5	chr2	113705011	113756693	-
SPDL1	chr5	169583636	169604778	+
TMSB4X	chrX	12975110	12977227	+
VPS53	chr17	508668	721717	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000120	chr1	117944807	118009049	+
hsa_circ_0001387	chr4	1902352	1936989	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004687.1	chr17	58330884	58332508	-
AC011815.1	chr18	35280867	35290201	-
AC126365.1	chr17	20788071	20789584	+
FGD5-AS1	chr3	14920347	14948424	-
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
AC138761.1	chr17	22266395	22288301	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia