exRNAdisease

Entry Detail

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General Information

Database ID: exR0196390 RNA Name: hsa-miR-144-3p RNA Type: miRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 28861548 End Site(bp): 28861567 External Links: hsa-miR-144-3p

Disease Information

Disease Name: Disease Category: MeSH ID: Type: Alias:

Expression Detail

GEO ID: GSE120584 Description: Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data Experimental Design: Disease vs Control Case Disease Type: Alzheimer's Disease Case Disease SubType: NA Case Sample: Alzheimer's Disease Control Sample: Normal Number of Case: 1021 Number of Control: 288 Number of Samples: 1309

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANXA2 chr15 60347134 60402883 - ARHGAP18 chr6 129576132 129710177 - CNOT11 chr2 101252886 101270316 + EPHA7 chr6 93240020 93419559 - G3BP2 chr4 75642782 75724525 - GABPB1 chr15 50275392 50355408 - IKZF2 chr2 212999691 213152427 - RAB15 chr14 64945814 64973226 - ROCK2 chr2 11179759 11348330 - SGPP1 chr14 63684216 63728065 - USP47 chr11 11841423 11961887 + ZNF695 chr1 246945547 247008093 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001376 chr3 194169185 194175121 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010980.2 chr2 222317242 222318653 - AC022167.2 chr16 8848105 8860456 + AC093010.3 chr3 114314501 114329714 - AF254983.1 chr21 10482738 10605716 + ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - EBLN3P chr9 37079645 37090928 + HCG11 chr6 26521709 26527404 + LINC00662 chr19 27681072 27794005 - MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - OTUD6B-AS1 chr8 91059318 91070583 - SDCBP2-AS1 chr20 1325405 1378735 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE120584 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2532 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30820472 Title: Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data Author: Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S Journal: Commun Biol. 2019 Feb 25;2:77. Description: we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia