exRNAdisease

Entry Detail

General Information

Database ID:

exR0196393

RNA Name:

hsa-miR-145-5p

RNA Type:

miRNA

Chromosome:

chr5

Starnd:

+

Coordinate:

Start Site(bp):

149430661

End Site(bp):

149430683

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACBD5	chr10	27195214	27242130	-
ATP9A	chr20	51596514	51768390	-
BAZ1B	chr7	73440406	73522293	-
CARMIL1	chr6	25279078	25620530	+
CCNJ	chr10	96043394	96060870	+
MYRF	chr11	61752642	61788518	+
PLEKHM1	chr17	45435900	45490749	-
PPP1R9B	chr17	50133737	50150677	-
RAD23B	chr9	107283137	107332192	+
ZNF28	chr19	52797408	52857600	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001454	chr4	154524454	154533552	+
hsa_circ_0000540	chr14	55799534	55821940	+
hsa_circ_0001731	chr7	100731990	100738448	+
hsa_circ_0001492	chr5	65284462	65290692	+
hsa_circ_0001414	chr4	56277780	56284152	+
hsa_circ_0000943	chr19	47421744	47440665	+
hsa_circ_0001168	chr20	47691321	47707559	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC006064.5	chr12	6510275	6510522	+
AC016876.2	chr17	7581964	7584086	-
AC023509.1	chr12	53441741	53467528	+
AC105339.2	chr15	82752884	82757208	+
AC144548.1	chr12	110387463	110445548	-
AL031282.2	chr1	1702736	1737688	-
JPX	chrX	73944182	74070408	+
KCNQ1OT1	chr11	2608328	2699994	-
LINC00852	chr3	10284419	10285746	+
MALAT1	chr11	65497688	65506516	+
MEG3	chr14	100779410	100861031	+
SNHG1	chr11	62851984	62855953	-
TUG1	chr22	30969245	30979395	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia