exRNAdisease

Entry Detail

General Information

Database ID:

exR0196403

RNA Name:

hsa-miR-147a

RNA Type:

miRNA

Chromosome:

chr9

Starnd:

-

Coordinate:

Start Site(bp):

120244985

End Site(bp):

120245004

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
TWF1	chr12	43793723	43806375	-
GLYR1	chr16	4803203	4847288	-
PLPP6	chr9	4662294	4665258	+
USP37	chr2	218450251	218568351	-
CTSD	chr11	1752755	1764573	-
NUP58	chr13	25301556	25349800	+
JARID2	chr6	15246069	15522042	+
SCARB1	chr12	124776856	124882668	-
MGRN1	chr16	4616493	4690974	+
CRKL	chr22	20917407	20953747	+
SIPA1L3	chr19	37907208	38208369	+
TIMP3	chr22	32801701	32863043	+
SNAI2	chr8	48917598	48921740	-
FAM13A	chr4	88725955	89111398	-
ZNF618	chr9	113876282	114056591	+
SMIM12	chr1	34712737	34859755	-
CCND1	chr11	69641156	69654474	+
FOXK2	chr17	82519713	82644662	+
SLC7A1	chr13	29509414	29595688	-
ATP11A	chr13	112690329	112887168	+
PSME3	chr17	42824385	42843760	+
WIZ	chr19	15419978	15449956	-
PURA	chr5	140107777	140125619	+
STARD7	chr2	96184859	96208825	-
OSBPL9	chr1	51577179	51798427	+
PIK3C2A	chr11	17077730	17207983	-
NKIRAS2	chr17	42011382	42025644	+
LIMD1	chr3	45555394	45686341	+
TNFRSF10B	chr8	23020133	23069031	-
ARHGAP35	chr19	46860997	47005077	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000816	chr17	80521229	80526077	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004951.4	chr7	43951910	44019151	-
AC010442.1	chr5	466124	473098	-
AL355987.2	chr9	136800366	136829466	+
DSCAM-AS1	chr21	40383083	40385358	+
KCNQ1OT1	chr11	2608328	2699994	-
MIR503HG	chrX	134543119	134546642	-
NEAT1	chr11	65422774	65445540	+
POLR2J4	chr7	43940895	44019175	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia