exRNAdisease

Entry Detail

General Information

Database ID:

exR0196426

RNA Name:

hsa-miR-155-3p

RNA Type:

miRNA

Chromosome:

chr21

Starnd:

+

Coordinate:

Start Site(bp):

25574022

End Site(bp):

25574043

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADCY3	chr2	24819169	24919839	-
OTUB1	chr11	63985853	64001811	+
AC245033.1	chr15	82536788	82573194	-
DDB1	chr11	61299451	61342596	-
HLA-DRA	chr6	32439878	32445046	+
RPL37A	chr2	216498825	216579180	+
RPS15	chr19	1438358	1440494	+
RPS17	chr15	82536750	82540459	-
TMEM106C	chr12	47963569	47968878	+
XAB2	chr19	7619525	7629545	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC245033.4	chr15	82533175	82540008	-
MIR155HG	chr21	25561909	25575168	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia