exRNAdisease

Entry Detail

General Information

Database ID:

exR0196532

RNA Name:

hsa-miR-206

RNA Type:

miRNA

Chromosome:

chr6

Starnd:

+

Coordinate:

Start Site(bp):

52144401

End Site(bp):

52144422

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CAPNS1	chr19	36139953	36150353	+
NPEPPS	chr17	47522942	47623276	+
SPRED1	chr15	38252836	38357249	+
SLC30A7	chr1	100896076	100981757	+
DDX5	chr17	64498254	64508199	-
TRIM2	chr4	153152342	153339317	+
DLG3	chrX	70444835	70505490	+
LASP1	chr17	38869859	38921770	+
RTL8B	chrX	135020513	135022542	-
FOXP1	chr3	70952817	71583993	-
SDCBP	chr8	58552924	58582859	+
NME1-NME2	chr17	51153590	51171744	+
NR2C2	chr3	14947584	15053600	+
TNRC6B	chr22	40044817	40335808	+
CREB3L2	chr7	137874979	138002086	-
NETO2	chr16	47077703	47143945	-
ZNF518A	chr10	96129715	96205288	+
PGM2	chr4	37826660	37862937	+
PRR12	chr19	49591182	49626439	+
PTBP1	chr19	797075	812327	+
CALM1	chr14	90396502	90408268	+
NME2	chr17	51165435	51171747	+
AP1S1	chr7	101154456	101161596	+
MAPK1	chr22	21754500	21867680	-
GID4	chr17	18039408	18068405	+
SMCO4	chr11	93478472	93543391	-
SS18	chr18	26016253	26091217	-
CWC15	chr11	94962620	94973586	-
WIPF2	chr17	40219304	40284136	+
WDR5	chr9	134135365	134159968	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000816	chr17	80521229	80526077	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005332.7	chr17	68188547	68189165	+
AC145207.5	chr17	81878425	81881106	-
LINC00641	chr14	21200079	21206900	-
MALAT1	chr11	65497688	65506516	+
MIR4435-2HG	chr2	111006015	111523376	-
NEAT1	chr11	65422774	65445540	+
RMRP	chr9	35657751	35658018	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia