exRNAdisease

Entry Detail

General Information

Database ID:

exR0196623

RNA Name:

hsa-miR-296-5p

RNA Type:

miRNA

Chromosome:

chr20

Starnd:

-

Coordinate:

Start Site(bp):

58817661

End Site(bp):

58817681

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACTN4	chr19	38647649	38731589	+
CBX1	chr17	48070052	48101478	-
EPHB4	chr7	100802565	100827523	-
FOXP4	chr6	41546426	41602384	+
GOSR2	chr17	46923075	46975524	+
RFX1	chr19	13961530	14007039	-
WDR5	chr9	134135365	134159968	+
ZCCHC3	chr20	297570	300321	+
GNL1	chr6	30541377	30557174	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC016876.2	chr17	7581964	7584086	-
AL132655.2	chr20	58817132	58817725	-
AL355075.4	chr14	20343048	20343685	-
AL356488.2	chr1	109100193	109100619	+
KCNQ1OT1	chr11	2608328	2699994	-
MIR34AHG	chr1	9148011	9198906	-
MIR663AHG	chr20	26167817	26251546	-
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
STAG3L5P-PVRIG2P-PILRB	chr7	100336104	100367831	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia