exRNAdisease

Entry Detail

General Information

Database ID:

exR0196965

RNA Name:

hsa-miR-377-3p

RNA Type:

miRNA

Chromosome:

chr14

Starnd:

+

Coordinate:

Start Site(bp):

101062094

End Site(bp):

101062115

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ATP9A	chr20	51596514	51768390	-
CLDN11	chr3	170418865	170454733	+
ETS1	chr11	128458761	128587558	-
GPR180	chr13	94601857	94634661	+
IGF1R	chr15	98648539	98964530	+
IRX3	chr16	54283304	54286787	-
MET	chr7	116672196	116798386	+
PALLD	chr4	168497052	168928457	+
PTBP3	chr9	112217716	112333667	-
RNMT	chr18	13726660	13764558	+
RUNX1	chr21	34787801	36004667	-
USP31	chr16	23061406	23149270	-
WDR82	chr3	52254434	52288020	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000712	chr16	68208276	68225678	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC016876.2	chr17	7581964	7584086	-
AC021078.1	chr5	149494314	149504670	-
AL137129.1	chr14	61734138	61776260	+
AL356488.2	chr1	109100193	109100619	+
CKMT2-AS1	chr5	81201341	81301565	-
KCNQ1OT1	chr11	2608328	2699994	-
MIR17HG	chr13	91347820	91354579	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
SNHG1	chr11	62851984	62855953	-
SNHG16	chr17	76557764	76565348	+
SNHG5	chr6	85650491	85678932	-
STAG3L5P-PVRIG2P-PILRB	chr7	100336104	100367831	+
VPS9D1-AS1	chr16	89711856	89718165	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia