exRNAdisease

Entry Detail

General Information

Database ID:

exR0198018

RNA Name:

hsa-miR-616-3p

RNA Type:

miRNA

Chromosome:

chr12

Starnd:

-

Coordinate:

Start Site(bp):

57519183

End Site(bp):

57519204

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AL138752.2	chr9	37588413	38068687	-
GOSR1	chr17	30477362	30527592	+
NCOA3	chr20	47501887	47656877	+
TFB1M	chr6	155256134	155314493	-
TMEM123	chr11	102396332	102470384	-
TNPO1	chr5	72816312	72916733	+
TNRC6B	chr22	40044817	40335808	+
TOMM5	chr9	37582646	37592604	-
USP22	chr17	20999596	21043760	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001731	chr7	100731990	100738448	+
hsa_circ_0001136	chr20	30954186	30956926	+
hsa_circ_0000943	chr19	47421744	47440665	+
hsa_circ_0000398	chr12	46633461	46637097	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007952.4	chr17	19112000	19112636	-
NEAT1	chr11	65422774	65445540	+
PSMA3-AS1	chr14	58265365	58298134	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia